High-Throughput Approaches to Pinpoint Function within the Noncoding Genome
نویسندگان
چکیده
منابع مشابه
High-Throughput Approaches to Pinpoint Function within the Noncoding Genome.
The clustered regularly interspaced short palindromic repeats (CRISPR)-Cas nuclease system is a powerful tool for genome editing, and its simple programmability has enabled high-throughput genetic and epigenetic studies. These high-throughput approaches offer investigators a toolkit for functional interrogation of not only protein-coding genes but also noncoding DNA. Historically, noncoding DNA...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2017
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2017.09.017